TogoDX/human is a new application for the integrated exploration of life science data on humans.

We are pleased to announce that the addition of 14 new attributes and that “Ensembl transcript” can now be selected as the target dataset for the exploration. In addition, we have just updated the data for the 10 original sources used to create the existing attributes.
For details, please see below.

Overview of addition of new attributes and data updates for TogoDX/Human (v2022-11)

• New added attributes
  • Gene
    • Ortholog existence
    • Biological process
    • Cellular component
    • Molecular function
    • Transcript biotype
    • Transcript length
  • Protein
    • UniProtKB sections
    • Isoform specific GO existence
    • Catalytic activity
    • Isoform specific interaction existence
    • Pathway annotation
  • Structure
    • # of turn structures
    • # of disulfide bonds
    • Rate of disorder regions
• New target dataset
  • Ensembl transcript
• Updated original sources
  • Ensembl (human release 107)
  • UniProt (release 2022_03)
  • PDB (2022-09-28 updated)
  • Reactome (76)
  • ChEMBL (CHEMBL31)
  • ChEBI (Release 213)
  • Mondo Disease Ontology (v2022-08-01)
  • MeSH (2022-09-20 updated)
  • GWAS Catalog All associations (2022-09-20 updated)
  • ClinVar (2022-09-01 updated)