A paper “CRISPR-Cas3 induces broad and unidirectional genome editing in human cells” was published in Nature Communications. Dr. Yuki Naito of DBCLS has contributed to this work in exhaustive off-target searches using GGGenome (https://GGGenome.dbcls.jp/), fast and accurate sequence search software developed by DBCLS.

The open-access full paper can be found online at:
https://doi.org/10.1038/s41467-019-13226-x

Morisaka H, Yoshimi K, Okuzaki Y, Gee P, Kunihiro Y, Sonpho E, Xu H, Sasakawa N, Naito Y, Nakada S, Yamamoto T, Sano S, Hotta A, Takeda J, Mashimo T. CRISPR-Cas3 induces broad and unidirectional genome editing in human cells. Nature Comminucations 10, 5302 (2019). DOI: 10.1038/s41467-019-13226-x