TogoVar, the integrated database for human genome variants (https://togovar.org/), continues to implement new features and expand its data. We are pleased to announce the following new features:

• Mappings between mouse variants in MoG+ (Mouse genome database with high added value) and human variants in TogoVar, are now available on gene pages (e.g., BRCA2 gene). These mappings are based on the UCSC Chain File. You can now search for laboratory mouse strains that carry variants corresponding to human missense or pathogenic variants. MoG+ is developed and maintained by RIKEN BioResource Research Center.
• Protein Browser has been added to the gene pages (e.g., BRCA2 gene). The following data are aligned along an amino acid sequence to facilitate comparison:
  • Missense variants and their pathogenicity (Source: TogoVar)
  • Phosphorylation sites (Source: jPOST: Japan ProteOme STandard Repository/Database)
  • Glycosylation sites (Source: GlyCosmos: Glycoscience Portal)
  • Disease-related variants (Source: UniProt)
• The URL specification method was extended on the variant pages. For example, the page for tgv47264307 can now be displayed using the following URLs:
  • By chromosome number, base position, reference allele, and alternate allele:
    • https://grch38.togovar.org/variant/12-111803962-G-A
  • By dbSNP rs number:
    • https://grch38.togovar.org/variant/rs671